Equine leptospirosis is caused by spiral bacteria from the genus Leptospira spp. The bacteria can colonize in the kidneys and travel throughout the bloodstream,3 causing uveitis (inflammation of the uveal tract in the eye) as well as abortions and kidney failure.3-5
TRANSMISSION: bacterial exposure via contact with urine from infected wildlife, cattle and dogs, or contact with standing water containing the bacteria
CLINICAL SIGNS: fever, depression, loss of appetite, frequent blinking and tearing of the eyes, abortion, increased drinking and urinating, bloody urine
PROGNOSIS: infection can result in abortions and kidney failure can be fatal. For horses with equine recurrent uveitis (ERU), symptoms must be managed for the duration of the horse’s life and may result in blindness.
ZOONOTIC POTENTIAL: can be transmitted from horses to humans6
PREVENTION: initial series of vaccinations with LEPTO EQ INNOVATOR® followed by annual revaccination*
*Currently, there are no vaccines available with USDA-licensed label claims against equine abortions, uveitis or acute renal failure due to L. pomona.
3 Divers TJ, Chang Y-F. Leptospirosis. In: Robinson NE, Sprayberry KA, eds. Current Therapy in Equine Medicine. Vol 6. 6th ed. St. Louis, MO: Saunders Elsevier 2009:145-147.
4 Data on file, Study Report No. Restricted Grant-FTLEPTO13 (v1.0) TI-01366, Zoetis Inc.
5 Thomas H. Leptospirosis in horses. Equine Chronicle. January/February 2015. http://www.equinechronicle.com/ leptospirosis-in-horses. Accessed November 30, 2016.
6 Bharti AR, Nally JE, Ricaldi JN, et al. Leptospirosis: a zoonotic disease of global importance. Lancet Infect Dis. 2003;3(12):757–771.