GBED RESULTS
Glycogen Branching Enzyme Deficiency (GBED)
Choose your horse’s result for more information.
N/N Results
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What do these results mean for my horse?
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N/N Results
Your horse did not inherit the GBED mutation and is considered normal.
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What are the symptoms of GBED?
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- Extreme muscle weakness.
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- Foals struggle to stand or nurse unassisted.
- Low body temperature at birth.
- Seizures.
- Lethargy.
- Contracted tendons on all four limbs.
- Respiratory and/or heart failure.
- Foals are most often aborted or still born.
- Foals that survive past birth are euthanized due to poor quality of life.
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How can GBED be prevented?
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Due to GBED being fatal for homozygous (G/G) horses, the only way to manage it is with responsible breeding. Carefully considering the health panel results of a mare and stallion when breeding is critical in preventing this disorder.
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How does this affect breeding decisions?
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When breeding any horse, probability of offspring inheriting genetic mutations should always be considered. This is especially crucial with GBED as it is a fatal recessive disease.
Expected breeding outcomes are shown below. A normal GBED gene is indicated by "N". A mutated GBED gene is indicated by "G".
100% chance of a foal who will not carry GBED and is considered normal. They cannot pass on the mutation to offspring themselves.
50% chance of a foal who will not carry GBED and is considered normal. They cannot pass on the mutation to offspring themselves.
50% chance of a foal who is a carrier and inherits one copy of GBED. This horse will appear normal, but can pass on the GBED mutation to offspring.
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N/G Results
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What do these results mean for my horse?
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N/G Results
Your horse inherited one copy of GBED and will appear normal for this disease. Your horse is known as a carrier for GBED. They are not known to be affected by the mutation but can pass it on to offspring.
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What are the symptoms of GBED?
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- Extreme muscle weakness.
-
- Foals struggle to stand or nurse unassisted.
- Low body temperature at birth.
- Seizures.
- Lethargy.
- Contracted tendons on all four limbs.
- Respiratory and/or heart failure.
- Foals are most often aborted or still born.
- Foals that survive past birth are euthanized due to poor quality of life.
-
-
How can GBED be prevented?
-
Due to GBED being fatal for homozygous (G/G) horses, the only way to manage it is with responsible breeding. Carefully considering the health panel results of a mare and stallion when breeding is critical in preventing this disorder.
-
-
How does this affect breeding decisions?
-
When breeding any horse, probability of offspring inheriting genetic mutations should always be considered. This is especially crucial with GBED as it is a fatal recessive disease.
Expected breeding outcomes are shown below. A normal GBED gene is indicated by "N". A mutated GBED gene is indicated by "G".
50% chance of a foal who will not carry GBED and is considered normal. They cannot pass on the mutation to offspring themselves.
50% chance of a foal who is a carrier and inherits one copy of GBED. This horse will appear normal, but can pass on the GBED mutation to offspring.
25% chance of a foal who will not carry a copy of GBED and is considered normal. They cannot pass on the mutation to offspring themselves. However, if this horse is used for breeding, depending on the other parent’s health panel results, their offspring could still inherit the mutation.
50% chance of a foal who is a carrier and inherits one copy of GBED. This horse will appear normal, but can pass on the GBED mutation to offspring.
25% chance of a foal who inherits two copies of GBED and will die from the disorder.
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G/G Results
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What do these results mean for my horse?
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G/G Results
Your horse inherited two copies of GBED. They will be affected and will not survive past a few months of age and therefore cannot pass the mutation on to offspring.
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What are the symptoms of GBED?
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- Extreme muscle weakness.
-
- Foals struggle to stand or nurse unassisted.
- Low body temperature at birth.
- Seizures.
- Lethargy.
- Contracted tendons on all four limbs.
- Respiratory and/or heart failure.
- Foals are most often aborted or still born.
- Foals that survive past birth are euthanized due to poor quality of life.
-
-
How can GBED be prevented?
-
Due to GBED being fatal for homozygous (G/G) horses, the only way to manage it is with responsible breeding. Carefully considering the health panel results of a mare and stallion when breeding is critical in preventing this disorder.
-
-
How does this affect breeding decisions?
-
When breeding any horse, probability of offspring inheriting genetic mutations should always be considered. This is especially crucial with GBED as it is a fatal recessive disease.
Expected breeding outcomes are shown below. A normal GBED gene is indicated by "N". A mutated GBED gene is indicated by "G".
Horses with G/G result will be affected. Due to GBED being fatal in these horses (G/G), there are no breeding outcomes to consider as the foals will not survive to breeding age.
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Learn More